Involvement of the Coronary Bed in Patients with Coronary Heart Disease against the Background of Primarily Coronary and Generalized Atherosclerosis
- 作者: Bakarev M.1, Karpova A.1, Pichigin V.1, Nikityuk D.1, Lushnikova E.1
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隶属关系:
- Institute of Molecular Pathology and Pathomorphology
- 期: 卷 162, 编号 2 (2016)
- 页面: 283-287
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238125
- DOI: https://doi.org/10.1007/s10517-016-3595-8
- ID: 238125
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详细
Significant associations between clinical history factors, lipid metabolism parameters, and type of atherosclerotic process (area of vascular lesions and severity of clinical manifestations) were detected. The predominance of generalized atherosclerosis in chronic coronary heart disease group was associated with patients’ age, more incident excessive body weight and type 2 diabetes mellitus, and more severe course of arterial hypertension. Increased lipid spectrum atherogenicity was significantly more often observed in generalized atherosclerosis in the myocardial infarction group. Angiography and postmortem examination of coronary arteries detected two trends of atherogenic remodeling of the coronary vessels: more pronounced stenosis of the main vessels in autopsy specimens from myocardial infarction patients with mainly coronary atherosclerosis and more extensive coronary bed involvement in chronic coronary heart disease patients with generalized atherosclerosis.
作者简介
M. Bakarev
Institute of Molecular Pathology and Pathomorphology
编辑信件的主要联系方式.
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
A. Karpova
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
V. Pichigin
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
D. Nikityuk
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
E. Lushnikova
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk