Evaluation of Hemodynamic Significance of Stenosis in Multiple Involvement of the Coronary Vessels by Mathematical Simulation
- 作者: Simakov S.1,2, Gamilov T.1,3, Kopylov F.3,2, Vasilevskii Y.1,3
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隶属关系:
- Moscow Institute of Physics and Technology (MIPT)
- I. M. Sechenov First Moscow State Medical University
- Institute of Numerical Mathematics, Russian Academy of Sciences
- 期: 卷 162, 编号 1 (2016)
- 页面: 111-114
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237962
- DOI: https://doi.org/10.1007/s10517-016-3558-0
- ID: 237962
如何引用文章
详细
We use a mathematical model of one-dimensional blood flow in a network of blood vessels for in silico evaluation of hemodynamic significance of stenoses in multivessel coronary disease. Two cases were addressed: two stenosed vessels with different diameters and with the same degree of occlusion and two consecutive stenoses in the same vessel. We show that two criteria for the evaluation of hemodynamic significance based on the degree of stenosis and based on fractional flow reserve can give contradictory indications for surgical intervention. We also show that fractional flow reserve computation originally proposed for a single stenosis should be modified in the case of multivessel stenotic disease.
作者简介
S. Simakov
Moscow Institute of Physics and Technology (MIPT); I. M. Sechenov First Moscow State Medical University
编辑信件的主要联系方式.
Email: simakov.ss@mipt.ru
俄罗斯联邦, Moscow; Moscow
T. Gamilov
Moscow Institute of Physics and Technology (MIPT); Institute of Numerical Mathematics, Russian Academy of Sciences
Email: simakov.ss@mipt.ru
俄罗斯联邦, Moscow; Moscow
F. Kopylov
Institute of Numerical Mathematics, Russian Academy of Sciences; I. M. Sechenov First Moscow State Medical University
Email: simakov.ss@mipt.ru
俄罗斯联邦, Moscow; Moscow
Yu. Vasilevskii
Moscow Institute of Physics and Technology (MIPT); Institute of Numerical Mathematics, Russian Academy of Sciences
Email: simakov.ss@mipt.ru
俄罗斯联邦, Moscow; Moscow
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