Evaluation of Hemodynamic Significance of Stenosis in Multiple Involvement of the Coronary Vessels by Mathematical Simulation
- Авторы: Simakov S.1,2, Gamilov T.1,3, Kopylov F.3,2, Vasilevskii Y.1,3
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Учреждения:
- Moscow Institute of Physics and Technology (MIPT)
- I. M. Sechenov First Moscow State Medical University
- Institute of Numerical Mathematics, Russian Academy of Sciences
- Выпуск: Том 162, № 1 (2016)
- Страницы: 111-114
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237962
- DOI: https://doi.org/10.1007/s10517-016-3558-0
- ID: 237962
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Аннотация
We use a mathematical model of one-dimensional blood flow in a network of blood vessels for in silico evaluation of hemodynamic significance of stenoses in multivessel coronary disease. Two cases were addressed: two stenosed vessels with different diameters and with the same degree of occlusion and two consecutive stenoses in the same vessel. We show that two criteria for the evaluation of hemodynamic significance based on the degree of stenosis and based on fractional flow reserve can give contradictory indications for surgical intervention. We also show that fractional flow reserve computation originally proposed for a single stenosis should be modified in the case of multivessel stenotic disease.
Об авторах
S. Simakov
Moscow Institute of Physics and Technology (MIPT); I. M. Sechenov First Moscow State Medical University
Автор, ответственный за переписку.
Email: simakov.ss@mipt.ru
Россия, Moscow; Moscow
T. Gamilov
Moscow Institute of Physics and Technology (MIPT); Institute of Numerical Mathematics, Russian Academy of Sciences
Email: simakov.ss@mipt.ru
Россия, Moscow; Moscow
F. Kopylov
Institute of Numerical Mathematics, Russian Academy of Sciences; I. M. Sechenov First Moscow State Medical University
Email: simakov.ss@mipt.ru
Россия, Moscow; Moscow
Yu. Vasilevskii
Moscow Institute of Physics and Technology (MIPT); Institute of Numerical Mathematics, Russian Academy of Sciences
Email: simakov.ss@mipt.ru
Россия, Moscow; Moscow
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