Effect of Acute Emotional Stress on Proteomic Profile of Selected Brain Areas and Lysosomal Proteolysis in Rats with Different Behavioral Activity
- 作者: Sharanova N.1, Kirbaeva N.1, Toropygin I.2, Khryapova E.2, Koplik E.3, Soto C.1, Pertsov S.3, Vasiliev A.1
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隶属关系:
- Institute of Nutrition of Russian Academy of Medical Sciences
- Human Proteome, Center of Common Use, V. N. Orekhovich Research Institute of Biomedical Chemistry
- P. K. Anokhin Research Institute of Normal Physiology
- 期: 卷 161, 编号 3 (2016)
- 页面: 355-358
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237414
- DOI: https://doi.org/10.1007/s10517-016-3413-3
- ID: 237414
如何引用文章
详细
We compared proteome profiles of selected brain areas (cortex, amygdala, hippocampus, and reticular formation) and measured cathepsins B and D activity in liver lysosomal fraction in rats with different behavioral activity under conditions of emotional stress. In passive rats, the expression of some proteins in various brain regions was changed and baseline cathepsin B activity was higher than in active animals. Taken together, the results attest to differences in the adaptive response formation in rats, depending on behavioral features.
作者简介
N. Sharanova
Institute of Nutrition of Russian Academy of Medical Sciences
编辑信件的主要联系方式.
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
N. Kirbaeva
Institute of Nutrition of Russian Academy of Medical Sciences
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
I. Toropygin
Human Proteome, Center of Common Use, V. N. Orekhovich Research Institute of Biomedical Chemistry
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
E. Khryapova
Human Proteome, Center of Common Use, V. N. Orekhovich Research Institute of Biomedical Chemistry
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
E. Koplik
P. K. Anokhin Research Institute of Normal Physiology
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
C. Soto
Institute of Nutrition of Russian Academy of Medical Sciences
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
S. Pertsov
P. K. Anokhin Research Institute of Normal Physiology
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
A. Vasiliev
Institute of Nutrition of Russian Academy of Medical Sciences
Email: sharanova@ion.ru
俄罗斯联邦, Moscow
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