Expression of Bax Protein and Morphological Changes in the Myocardium in Experimental Acute Pressure Overload of the Left Ventricle
- 作者: Blagonravov M.1, Korshunova A.1, Azova M.2, Bryk A.1, Frolov V.1
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隶属关系:
- Department of Pathology and Pathological Physiology
- Department of Biology and Common Genetics, Medical Institute, Russian, University of Peoples’ Friendship
- 期: 卷 161, 编号 2 (2016)
- 页面: 312-315
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237373
- DOI: https://doi.org/10.1007/s10517-016-3403-5
- ID: 237373
如何引用文章
详细
The expression of Bax protein, marker of intracellular pathway of apoptosis initiation, in viable left ventricular cardiomyocytes and morphological changes in the myocardium in acute pressure overload of the left ventricle were studied in experiment on male rabbits. The content of Bax protein in the cardiomyocyte cytoplasm decreased, this indicating that the mitochondrial pathway was not involved in the realization of the apoptotic program. This decrease was associated with manifest destructive changes in the left ventricular myocardium.
作者简介
M. Blagonravov
Department of Pathology and Pathological Physiology
Email: blagonravovm@mail.ru
俄罗斯联邦, Moscow
A. Korshunova
Department of Pathology and Pathological Physiology
Email: blagonravovm@mail.ru
俄罗斯联邦, Moscow
M. Azova
Department of Biology and Common Genetics, Medical Institute, Russian, University of Peoples’ Friendship
编辑信件的主要联系方式.
Email: blagonravovm@mail.ru
俄罗斯联邦, Moscow
A. Bryk
Department of Pathology and Pathological Physiology
Email: blagonravovm@mail.ru
俄罗斯联邦, Moscow
V. Frolov
Department of Pathology and Pathological Physiology
Email: blagonravovm@mail.ru
俄罗斯联邦, Moscow
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