Dose Dependence of the Anticoagulant Effect of Intravenously Administered Cellulose Sulfate
- 作者: Drozd N.1, Kuznetsova S.2, Kalinina T.1, Vasilieva N.2
-
隶属关系:
- Hematological Research Center, Ministry of Health of the Russian Federation
- Institute of Chemistry and Chemical Technology, Siberian Branch of the Russian Academy of Sciences
- 期: 卷 160, 编号 6 (2016)
- 页面: 767-770
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236935
- DOI: https://doi.org/10.1007/s10517-016-3305-6
- ID: 236935
如何引用文章
详细
Experiments on rabbits showed that increasing the dose of intravenously administered cellulose sulfate from wheat straw (dynamic viscosity 3.4 cP, sulfur content 14.1%) increased plasma clotting time in some coagulation tests and plasma anticoagulant activity. When cellulose sulfate was administered in the dose of 1 mg/kg, plasma clotting time in the presence of the anticoagulant (5 min after administration) was ~3-fold higher than after saline administration.
作者简介
N. Drozd
Hematological Research Center, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: nndrozd@mail.ru
俄罗斯联邦, Moscow
S. Kuznetsova
Institute of Chemistry and Chemical Technology, Siberian Branch of the Russian Academy of Sciences
Email: nndrozd@mail.ru
俄罗斯联邦, Krasnoyarsk
T. Kalinina
Hematological Research Center, Ministry of Health of the Russian Federation
Email: nndrozd@mail.ru
俄罗斯联邦, Moscow
N. Vasilieva
Institute of Chemistry and Chemical Technology, Siberian Branch of the Russian Academy of Sciences
Email: nndrozd@mail.ru
俄罗斯联邦, Krasnoyarsk