Short Peptides and Telomere Length Regulator Hormone Irisin
- 作者: Khavinson V.1,2, Kuznik B.3, Tarnovskaya S.2,4, Lin’kova N.2,4
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隶属关系:
- Russian Academy of Sciences, I. P. Pavlov Institute of Physiology
- St. Petersburg Institute of Bioregulation and Gerontology
- Chita State Medical Academy, Ministry of Health of the Russian Federation
- St. Petersburg State Polytechnological University
- 期: 卷 160, 编号 3 (2016)
- 页面: 347-349
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236703
- DOI: https://doi.org/10.1007/s10517-016-3167-y
- ID: 236703
如何引用文章
详细
Irisin produced by muscles during exercise and promoting fat burning also exhibits geroprotective effect and induces telomere elongation in normal somatic cells. Special attention is paid to studies of the role of peptides Lys-Glu, Glu-Asp-Arg, and Ala-Glu-Asp-Gly in epigenetic regulation of irisin content. The data suggest that the immunomodulatory peptide Lys-Glu and neuroprotective peptide Glu-Asp-Arg modulate the life span by modulating irisin gene expression.
作者简介
V. Khavinson
Russian Academy of Sciences, I. P. Pavlov Institute of Physiology; St. Petersburg Institute of Bioregulation and Gerontology
Email: linkova@gerontology.ru
俄罗斯联邦, Moskva; St. Petersburg
B. Kuznik
Chita State Medical Academy, Ministry of Health of the Russian Federation
Email: linkova@gerontology.ru
俄罗斯联邦, Chita
S. Tarnovskaya
St. Petersburg Institute of Bioregulation and Gerontology; St. Petersburg State Polytechnological University
Email: linkova@gerontology.ru
俄罗斯联邦, St. Petersburg; St. Petersburg
N. Lin’kova
St. Petersburg Institute of Bioregulation and Gerontology; St. Petersburg State Polytechnological University
编辑信件的主要联系方式.
Email: linkova@gerontology.ru
俄罗斯联邦, St. Petersburg; St. Petersburg
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