Evaluation of Antitumor Efficiency of High Intensity Radiation  169 Yb Source on Experimental Sarcoma M-1

S. E. Ulyanenko; S. N. Koryakin; A. A. Lychagin; M. N. Kuznetsova; V. I. Potetnya; L. N. Ulyanenko; A. I. Brovin

doi:10.1007/s10517-019-04466-4

Evaluation of Antitumor Efficiency of High Intensity Radiation ¹⁶⁹Yb Source on Experimental Sarcoma M-1

Авторы: Ulyanenko S.¹, Koryakin S.¹, Lychagin A.¹, Kuznetsova M.¹, Potetnya V.¹, Ulyanenko L.¹, Brovin A.¹
Учреждения:
1. A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Выпуск: Том 167, № 1 (2019)
Страницы: 84-86
Раздел: Article
URL: https://journals.rcsi.science/0007-4888/article/view/241470
DOI: https://doi.org/10.1007/s10517-019-04466-4
ID: 241470

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Аннотация

Rats with sarcoma M-1 were exposed to high dose rate irradiation with ¹⁶⁹Yb source. In 25 days after introduction of a trocar with sealed capsule with ¹⁶⁹Yb source into the tumor, complete tumor regression was observed in 70% animals. The results suggest feasibility of using ¹⁶⁹Yb source for high-dose rate brachytherapy and development of the personalized medicine approaches.