Evaluation of Antitumor Efficiency of High Intensity Radiation 169Yb Source on Experimental Sarcoma M-1
- Authors: Ulyanenko S.E.1, Koryakin S.N.1, Lychagin A.A.1, Kuznetsova M.N.1, Potetnya V.I.1, Ulyanenko L.N.1, Brovin A.I.1
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Affiliations:
- A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
- Issue: Vol 167, No 1 (2019)
- Pages: 84-86
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241470
- DOI: https://doi.org/10.1007/s10517-019-04466-4
- ID: 241470
Cite item
Abstract
Rats with sarcoma M-1 were exposed to high dose rate irradiation with 169Yb source. In 25 days after introduction of a trocar with sealed capsule with 169Yb source into the tumor, complete tumor regression was observed in 70% animals. The results suggest feasibility of using 169Yb source for high-dose rate brachytherapy and development of the personalized medicine approaches.
About the authors
S. E. Ulyanenko
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: korsenic@mail.ru
Russian Federation, Obninsk
S. N. Koryakin
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Author for correspondence.
Email: korsenic@mail.ru
Russian Federation, Obninsk
A. A. Lychagin
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: korsenic@mail.ru
Russian Federation, Obninsk
M. N. Kuznetsova
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: korsenic@mail.ru
Russian Federation, Obninsk
V. I. Potetnya
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: korsenic@mail.ru
Russian Federation, Obninsk
L. N. Ulyanenko
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: korsenic@mail.ru
Russian Federation, Obninsk
A. I. Brovin
A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: korsenic@mail.ru
Russian Federation, Obninsk