Ergoferon Increases IL-2 Production by Activated Lymphocytes
- Авторы: Kanareikina M.1, Alinkina E.1, Petrova A.1, Emel’yanova A.1, Gorbunov E.1, Tarasov S.2
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Учреждения:
- Materia Medica Holding Research-and-Production Company, Research Institute of General Pathology and Pathophysiology
- Laboratory of Physiologically Active Substances, Department of Molecular and Cellular Pathophysiology, Research Institute of General Pathology and Pathophysiology
- Выпуск: Том 166, № 6 (2019)
- Страницы: 744-746
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241330
- DOI: https://doi.org/10.1007/s10517-019-04431-1
- ID: 241330
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Аннотация
We studied the effects of Ergoferon on the production of antiviral cytokine IL-2 by type 1 CD4+T cells. Preincubation of Jurkat cells with Ergoferon increased IL-2 secretion by these cells after stimulation with phorbol 12-myristate 13-acetate/ionomycine in comparison with the placebo group. The data prove that Ergoferon is capable of activating cell cascades involved in the realization of the antiviral immune response.
Об авторах
M. Kanareikina
Materia Medica Holding Research-and-Production Company, Research Institute of General Pathology and Pathophysiology
Автор, ответственный за переписку.
Email: rad@materiamedica.ru
Россия, Moscow
E. Alinkina
Materia Medica Holding Research-and-Production Company, Research Institute of General Pathology and Pathophysiology
Email: rad@materiamedica.ru
Россия, Moscow
A. Petrova
Materia Medica Holding Research-and-Production Company, Research Institute of General Pathology and Pathophysiology
Email: rad@materiamedica.ru
Россия, Moscow
A. Emel’yanova
Materia Medica Holding Research-and-Production Company, Research Institute of General Pathology and Pathophysiology
Email: rad@materiamedica.ru
Россия, Moscow
E. Gorbunov
Materia Medica Holding Research-and-Production Company, Research Institute of General Pathology and Pathophysiology
Email: rad@materiamedica.ru
Россия, Moscow
S. Tarasov
Laboratory of Physiologically Active Substances, Department of Molecular and Cellular Pathophysiology, Research Institute of General Pathology and Pathophysiology
Email: rad@materiamedica.ru
Россия, Moscow