Correction of Cholinergic Abnormalities in Mnestic Processes with Diterpene Alkaloid Songorine
- Авторы: Nesterova Y.1, Povet’eva T.1, Suslov N.1, Zyuz’kov G.1, Zhdanov V.1, Fedorova Y.2, Kul’pin P.1, Shaposhnikov K.1
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Учреждения:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
- Kemerovo State Medical University
- Выпуск: Том 165, № 1 (2018)
- Страницы: 10-13
- Раздел: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/239934
- DOI: https://doi.org/10.1007/s10517-018-4087-9
- ID: 239934
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Аннотация
Repeated administration of songorine to mice restored mnestic processes impaired by scopolamine treatment, which manifested in improvement of CPAR conditioning and normalization of behavioral activity throughtout the observation period. This thearpeutical effect surpassed that of pyracetam used as the reference drug.
Об авторах
Yu. Nesterova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Автор, ответственный за переписку.
Email: nes-yulia@yandex.ru
Россия, Tomsk
T. Povet’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yulia@yandex.ru
Россия, Tomsk
N. Suslov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yulia@yandex.ru
Россия, Tomsk
G. Zyuz’kov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yulia@yandex.ru
Россия, Tomsk
V. Zhdanov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yulia@yandex.ru
Россия, Tomsk
Yu. Fedorova
Kemerovo State Medical University
Email: nes-yulia@yandex.ru
Россия, Kemerovo
P. Kul’pin
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yulia@yandex.ru
Россия, Tomsk
K. Shaposhnikov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yulia@yandex.ru
Россия, Tomsk