Focal Unilateral Traumatic brain injury Causes Delayed Neurodegenerative Changes in the Brain of Rats
- Авторы: Genrikhs E.1, Voronkov D.1, Kapkaeva M.1, Isaev N.1,2,3, Stelmashook E.1
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Учреждения:
- Research Center of Neurology, M. V. Lomonosov Moscow State University
- A. N. Belozersky Institute Of Physico-Chemical Biology, M. V. Lomonosov Moscow State University
- Faculty of Biology, M. V. Lomonosov Moscow State University
- Выпуск: Том 164, № 2 (2017)
- Страницы: 211-213
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239501
- DOI: https://doi.org/10.1007/s10517-017-3960-2
- ID: 239501
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Аннотация
A cascade of pathological changes in the intact hemisphere developed in rats 6 months after focal unilateral traumatic brain injury: neuronal degeneration, hyperexpression of α-synuclein, APP (β-amyloid peptide precursor) protein, and glutamine synthetase in cells other than astrocytes. The development of these changes in the contralateral hemisphere indicated the emergence of extensive delayed neurodegenerative processes in the brain after traumatic brain injury, which were characteristic of diseases associated with pathological aging.
Об авторах
E. Genrikhs
Research Center of Neurology, M. V. Lomonosov Moscow State University
Email: estelmash@mail.ru
Россия, Moscow
D. Voronkov
Research Center of Neurology, M. V. Lomonosov Moscow State University
Email: estelmash@mail.ru
Россия, Moscow
M. Kapkaeva
Research Center of Neurology, M. V. Lomonosov Moscow State University
Email: estelmash@mail.ru
Россия, Moscow
N. Isaev
Research Center of Neurology, M. V. Lomonosov Moscow State University; A. N. Belozersky Institute Of Physico-Chemical Biology, M. V. Lomonosov Moscow State University; Faculty of Biology, M. V. Lomonosov Moscow State University
Email: estelmash@mail.ru
Россия, Moscow; Moscow; Moscow
E. Stelmashook
Research Center of Neurology, M. V. Lomonosov Moscow State University
Автор, ответственный за переписку.
Email: estelmash@mail.ru
Россия, Moscow
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