Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography
- Авторы: Rogozinskaya E.1, Lyapina M.1
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Учреждения:
- Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University
- Выпуск: Том 164, № 2 (2017)
- Страницы: 170-172
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239450
- DOI: https://doi.org/10.1007/s10517-017-3950-4
- ID: 239450
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Аннотация
Thromboelastography revealed anticoagulant effects of 3 glyproline oligopeptides (in various concentrations): His-Phe-Arg-Trp-Pro-Gly-Pro, Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank), and Pro-Gly-Pro. The parameters R, K, MA, S, TMA, and J changed to hypocoagulation direction in comparison to the control. At this, Selank demonstrated the maximal anticoagulation potency.
Об авторах
E. Rogozinskaya
Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University
Автор, ответственный за переписку.
Email: elinamiss007@mail.ru
Россия, Moscow
M. Lyapina
Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University
Email: elinamiss007@mail.ru
Россия, Moscow