Stably Fluorescent Cell Line of Human Ovarian Epithelial Cancer Cells SK-OV-3ip-red
- Авторы: Konovalova E.1, Shulga A.1, Chumakov S.1, Khodarovich Y.1, Woo E.2, Deev S.1
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Учреждения:
- M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Korea Research Institute of Bioscience and Biotechnology (KRIBB)
- Выпуск: Том 164, № 1 (2017)
- Страницы: 99-101
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239392
- DOI: https://doi.org/10.1007/s10517-017-3933-5
- ID: 239392
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Аннотация
Stable red fluorescing line of human ovarian epithelial cancer cells SK-OV-3ip-red was generated expressing gene coding for protein TurboFP635 (Katushka) fluorescing in the far-red spectrum region with excitation and emission peaks at 588 and 635 nm, respectively. Fluorescence of SK-OV-3ip-red line remained high during long-term cell culturing and after cryogenic freezing. The obtained cell line SK-OV-3ip-red can serve a basis for a model of a scattered tumor with numerous/extended metastases and used both for testing anticancer drugs inhibiting metastasis growth and for non-invasive monitoring of the growth dynamics with high precision.
Об авторах
E. Konovalova
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: deyev@mx.ibch.ru
Россия, Moscow
A. Shulga
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: deyev@mx.ibch.ru
Россия, Moscow
S. Chumakov
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: deyev@mx.ibch.ru
Россия, Moscow
Yu. Khodarovich
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: deyev@mx.ibch.ru
Россия, Moscow
Eui-Jeon Woo
Korea Research Institute of Bioscience and Biotechnology (KRIBB)
Email: deyev@mx.ibch.ru
Республика Корея, Daejeon
S. Deev
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: deyev@mx.ibch.ru
Россия, Moscow