Отправить статью по E-mail Psychopharmacological Effects of JNK Inhibitor in Posthypoxic Encephalopathy and Mechanisms of Their Development
- Авторы: Zyuz’kov G.1,2, Suslov N.1, Povet’eva T.1, Nesterova Y.1, Afanas’eva O.1, Udut E.1, Miroshnichenko L.1, Simanina E.1, Polyakova T.1, Stavrova L.1, Chaikovskii A.1, Kul’pin P.1, Udut V.1,2, Dygai A.1, Zhdanov V.1
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Учреждения:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- Laboratory for Physical Processes Modeling in Biology and Medicine, National Research Tomsk State University
- Выпуск: Том 163, № 1 (2017)
- Страницы: 18-21
- Раздел: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/238615
- DOI: https://doi.org/10.1007/s10517-017-3727-9
- ID: 238615
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Аннотация
Psychopharmacological effects of JNK inhibitor were studied using a mouse model of posthypoxic encephalopathy. The preparation exhibited a pronounced cerebroprotective effect manifested in normalization of orientation and exploratory behavior and conditioned responses in posthypoxic mice. These effects were accompanied by marked elevation of neural stem cell content in the paraventricular region of the brain.
Об авторах
G. Zyuz’kov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; Laboratory for Physical Processes Modeling in Biology and Medicine, National Research Tomsk State University
Автор, ответственный за переписку.
Email: zgn@pharmso.ru
Россия, Tomsk; Tomsk
N. Suslov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
T. Povet’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
Yu. Nesterova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
O. Afanas’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
E. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
L. Miroshnichenko
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
E. Simanina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
T. Polyakova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
L. Stavrova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
A. Chaikovskii
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
P. Kul’pin
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
V. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; Laboratory for Physical Processes Modeling in Biology and Medicine, National Research Tomsk State University
Email: zgn@pharmso.ru
Россия, Tomsk; Tomsk
A. Dygai
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
V. Zhdanov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: zgn@pharmso.ru
Россия, Tomsk
