Cystatin C as a Marker of Progressing Cardiovascular Events during Coronary Heart Disease
- Авторы: Gevorgyan M.1, Voronina N.2, Goncharova N.1, Kozaruk T.2, Russkikh G.1, Bogdanova L.3, Korolenko T.1
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Учреждения:
- Research Institute of Physiology and Fundamental Medicine
- Research Institute of Biochemistry
- Research Institute of Molecular Pathology and Pathomorphology
- Выпуск: Том 162, № 4 (2017)
- Страницы: 421-424
- Раздел: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/238274
- DOI: https://doi.org/10.1007/s10517-017-3630-4
- ID: 238274
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Аннотация
The role of cystatin C, an inhibitor of cysteine proteases, as an alternative and potent predictor of acute cardiovascular events in coronary heart disease (CHD) patients was examined and compared to that of other markers of cardiorenal abnormalities. The patients with CHD demonstrated elevated serum cystatin C, especially in cases with serious risk of cardiovascular complications. In comparison with other indicators of cardiorenal dysfunction, cystatin C can be viewed as an alternative predictor of cardiovascular complications, although its sensitivity is inferior to that of high-sensitivity C-reactive protein and natriuretic peptide.
Об авторах
M. Gevorgyan
Research Institute of Physiology and Fundamental Medicine
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk
N. Voronina
Research Institute of Biochemistry
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk
N. Goncharova
Research Institute of Physiology and Fundamental Medicine
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk
T. Kozaruk
Research Institute of Biochemistry
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk
G. Russkikh
Research Institute of Physiology and Fundamental Medicine
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk
L. Bogdanova
Research Institute of Molecular Pathology and Pathomorphology
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk
T. Korolenko
Research Institute of Physiology and Fundamental Medicine
Автор, ответственный за переписку.
Email: t.a.korolenko@physiol.ru
Россия, Novosibirsk