Cystatin C as a Marker of Progressing Cardiovascular Events during Coronary Heart Disease
- Autores: Gevorgyan M.1, Voronina N.2, Goncharova N.1, Kozaruk T.2, Russkikh G.1, Bogdanova L.3, Korolenko T.1
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Afiliações:
- Research Institute of Physiology and Fundamental Medicine
- Research Institute of Biochemistry
- Research Institute of Molecular Pathology and Pathomorphology
- Edição: Volume 162, Nº 4 (2017)
- Páginas: 421-424
- Seção: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/238274
- DOI: https://doi.org/10.1007/s10517-017-3630-4
- ID: 238274
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Resumo
The role of cystatin C, an inhibitor of cysteine proteases, as an alternative and potent predictor of acute cardiovascular events in coronary heart disease (CHD) patients was examined and compared to that of other markers of cardiorenal abnormalities. The patients with CHD demonstrated elevated serum cystatin C, especially in cases with serious risk of cardiovascular complications. In comparison with other indicators of cardiorenal dysfunction, cystatin C can be viewed as an alternative predictor of cardiovascular complications, although its sensitivity is inferior to that of high-sensitivity C-reactive protein and natriuretic peptide.
Sobre autores
M. Gevorgyan
Research Institute of Physiology and Fundamental Medicine
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk
N. Voronina
Research Institute of Biochemistry
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk
N. Goncharova
Research Institute of Physiology and Fundamental Medicine
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk
T. Kozaruk
Research Institute of Biochemistry
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk
G. Russkikh
Research Institute of Physiology and Fundamental Medicine
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk
L. Bogdanova
Research Institute of Molecular Pathology and Pathomorphology
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk
T. Korolenko
Research Institute of Physiology and Fundamental Medicine
Autor responsável pela correspondência
Email: t.a.korolenko@physiol.ru
Rússia, Novosibirsk