New Experimental Model of Rat Risk Behavior. Effects of Nicotine and Phenazepam
- Авторы: Sudakov S.1, Nazarova G.1, Alekseeva E.1
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Учреждения:
- P. K. Anokhin Research Institute of Normal Physiology
- Выпуск: Том 162, № 3 (2017)
- Страницы: 409-411
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238262
- DOI: https://doi.org/10.1007/s10517-017-3627-z
- ID: 238262
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Аннотация
We described a new model of risk behavior in rats that allows selection of animals predisposed to risk behavior in the absence of other biological motivations. Phenazepam administration did not change the intensity of risk behavior in “risky” animals, but stimulated risk behavior in rats that were not predisposed to it. Nicotine inhibited risk behavior in “risky” animals and strengthened it in “cautious” rats. In the intermediate group, the drugs did not induce significant changes. A similar effect of the drugs was observed in the previous models. More complex effect of nicotine on the risk behavior may be explained by the absence of severe food motivation typical for the early models.
Об авторах
S. Sudakov
P. K. Anokhin Research Institute of Normal Physiology
Автор, ответственный за переписку.
Email: s-sudakov@nphys.ru
Россия, Moscow
G. Nazarova
P. K. Anokhin Research Institute of Normal Physiology
Email: s-sudakov@nphys.ru
Россия, Moscow
E. Alekseeva
P. K. Anokhin Research Institute of Normal Physiology
Email: s-sudakov@nphys.ru
Россия, Moscow