New Experimental Model of Rat Risk Behavior. Effects of Nicotine and Phenazepam
- Авторлар: Sudakov S.1, Nazarova G.1, Alekseeva E.1
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Мекемелер:
- P. K. Anokhin Research Institute of Normal Physiology
- Шығарылым: Том 162, № 3 (2017)
- Беттер: 409-411
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238262
- DOI: https://doi.org/10.1007/s10517-017-3627-z
- ID: 238262
Дәйексөз келтіру
Аннотация
We described a new model of risk behavior in rats that allows selection of animals predisposed to risk behavior in the absence of other biological motivations. Phenazepam administration did not change the intensity of risk behavior in “risky” animals, but stimulated risk behavior in rats that were not predisposed to it. Nicotine inhibited risk behavior in “risky” animals and strengthened it in “cautious” rats. In the intermediate group, the drugs did not induce significant changes. A similar effect of the drugs was observed in the previous models. More complex effect of nicotine on the risk behavior may be explained by the absence of severe food motivation typical for the early models.
Авторлар туралы
S. Sudakov
P. K. Anokhin Research Institute of Normal Physiology
Хат алмасуға жауапты Автор.
Email: s-sudakov@nphys.ru
Ресей, Moscow
G. Nazarova
P. K. Anokhin Research Institute of Normal Physiology
Email: s-sudakov@nphys.ru
Ресей, Moscow
E. Alekseeva
P. K. Anokhin Research Institute of Normal Physiology
Email: s-sudakov@nphys.ru
Ресей, Moscow
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