Reaction of Lymphoid Organs to Injection of Iron-Carbon Nanoparticles
- Авторы: Khramtsova Y.1,2, Tyumentseva N.1,3, Yushkov B.1,2,3, Silant’eva E.2, Medvedeva S.1,2,3, Byzov I.4, Uimin M.4, Ermakov A.4
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Учреждения:
- Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences
- B. N. Eltsin Ural Federal University
- Institute of Medical Cell Technologies
- M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences
- Выпуск: Том 162, № 2 (2016)
- Страницы: 252-254
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238090
- DOI: https://doi.org/10.1007/s10517-016-3588-7
- ID: 238090
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Аннотация
The distribution of iron-carbon nanoparticles in FeC-DSPE-PEG-2000 modification (micellar particles with structure (Fe) core-carbon shell; PEG-based coating) is studied. The greater part of the nanoparticles accumulated in the spleen and liver, a small amount in the lungs, and the minimum amount in the thymus. The structural changes in the lymphoid organs were minor and involved only the microcirculatory bed. Analysis of the peripheral blood showed manifest anemia, thrombocytopenia, and leukocytosis.
Об авторах
Yu. Khramtsova
Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; B. N. Eltsin Ural Federal University
Автор, ответственный за переписку.
Email: hramtsova15@mail.ru
Россия, Ekaterinburg; Ekaterinburg
N. Tyumentseva
Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; Institute of Medical Cell Technologies
Email: hramtsova15@mail.ru
Россия, Ekaterinburg; Ekaterinburg
B. Yushkov
Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; B. N. Eltsin Ural Federal University; Institute of Medical Cell Technologies
Email: hramtsova15@mail.ru
Россия, Ekaterinburg; Ekaterinburg; Ekaterinburg
E. Silant’eva
B. N. Eltsin Ural Federal University
Email: hramtsova15@mail.ru
Россия, Ekaterinburg
S. Medvedeva
Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; B. N. Eltsin Ural Federal University; Institute of Medical Cell Technologies
Email: hramtsova15@mail.ru
Россия, Ekaterinburg; Ekaterinburg; Ekaterinburg
I. Byzov
M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences
Email: hramtsova15@mail.ru
Россия, Ekaterinburg
M. Uimin
M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences
Email: hramtsova15@mail.ru
Россия, Ekaterinburg
A. Ermakov
M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences
Email: hramtsova15@mail.ru
Россия, Ekaterinburg
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