Reaction of Lymphoid Organs to Injection of Iron-Carbon Nanoparticles


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Resumo

The distribution of iron-carbon nanoparticles in FeC-DSPE-PEG-2000 modification (micellar particles with structure (Fe) core-carbon shell; PEG-based coating) is studied. The greater part of the nanoparticles accumulated in the spleen and liver, a small amount in the lungs, and the minimum amount in the thymus. The structural changes in the lymphoid organs were minor and involved only the microcirculatory bed. Analysis of the peripheral blood showed manifest anemia, thrombocytopenia, and leukocytosis.

Sobre autores

Yu. Khramtsova

Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; B. N. Eltsin Ural Federal University

Autor responsável pela correspondência
Email: hramtsova15@mail.ru
Rússia, Ekaterinburg; Ekaterinburg

N. Tyumentseva

Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; Institute of Medical Cell Technologies

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg; Ekaterinburg

B. Yushkov

Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; B. N. Eltsin Ural Federal University; Institute of Medical Cell Technologies

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg; Ekaterinburg; Ekaterinburg

E. Silant’eva

B. N. Eltsin Ural Federal University

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg

S. Medvedeva

Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; B. N. Eltsin Ural Federal University; Institute of Medical Cell Technologies

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg; Ekaterinburg; Ekaterinburg

I. Byzov

M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg

M. Uimin

M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg

A. Ermakov

M. N. Mikheev Institute of Metal Physics, the Ural Division of the Russian Academy of Sciences

Email: hramtsova15@mail.ru
Rússia, Ekaterinburg

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