Tumor Cell Behavior in Porous Hydrogels: Effect of Application Technique and Doxorubicin Treatment

M. H. Zoughaib; D. T. Luong; Z. Y. Siraeva; A. A. Yergeshov; T. I. Salikhova; S. V. Kuznetsova; R. G. Kiyamova; T. I. Abdullin

doi:10.1007/s10517-019-04577-y

Tumor Cell Behavior in Porous Hydrogels: Effect of Application Technique and Doxorubicin Treatment

Autores: Zoughaib M.¹, Luong D.¹, Siraeva Z.¹, Yergeshov A.¹, Salikhova T.¹, Kuznetsova S.¹, Kiyamova R.¹, Abdullin T.¹
Afiliações:
1. Kazan (Volga region) Federal University
Edição: Volume 167, Nº 4 (2019)
Páginas: 590-598
Seção: Article
URL: https://journals.rcsi.science/0007-4888/article/view/241942
DOI: https://doi.org/10.1007/s10517-019-04577-y
ID: 241942

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The effect of porosity on diffusion characteristics of scaffolds and invasive capacity of MCF-7 and PC-3 tumor cells was studied for gelatin hydrogels. According to MTS test results, the efficiency of population of a macroporous cryogel by cells applied by different techniques increased in the following order: migration from the monolayer