Tumor Cell Behavior in Porous Hydrogels: Effect of Application Technique and Doxorubicin Treatment

M. H. Zoughaib; D. T. Luong; Z. Y. Siraeva; A. A. Yergeshov; T. I. Salikhova; S. V. Kuznetsova; R. G. Kiyamova; T. I. Abdullin

doi:10.1007/s10517-019-04577-y

Tumor Cell Behavior in Porous Hydrogels: Effect of Application Technique and Doxorubicin Treatment

Authors: Zoughaib M.H.¹, Luong D.T.¹, Siraeva Z.Y.¹, Yergeshov A.A.¹, Salikhova T.I.¹, Kuznetsova S.V.¹, Kiyamova R.G.¹, Abdullin T.I.¹
Affiliations:
1. Kazan (Volga region) Federal University
Issue: Vol 167, No 4 (2019)
Pages: 590-598
Section: Article
URL: https://journals.rcsi.science/0007-4888/article/view/241942
DOI: https://doi.org/10.1007/s10517-019-04577-y
ID: 241942

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Abstract

The effect of porosity on diffusion characteristics of scaffolds and invasive capacity of MCF-7 and PC-3 tumor cells was studied for gelatin hydrogels. According to MTS test results, the efficiency of population of a macroporous cryogel by cells applied by different techniques increased in the following order: migration from the monolayer