Enviar artigo por via de e-mail Influence of Age Factor on Respiratory Control of Isolated Cardiomyocytes and Mitochondria in Rats
- Autores: Tsapko L.1, Afanas’ev S.1
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Afiliações:
- Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
- Edição: Volume 167, Nº 4 (2019)
- Páginas: 452-454
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241792
- DOI: https://doi.org/10.1007/s10517-019-04547-4
- ID: 241792
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Resumo
We studied the peculiarities of oxidative and substrate phosphorylation in isolated cardiomyocytes and myocardial mitochondria in 2- and 15-month-old rats. It was shown that age factor reduces the degree of oxidation and phosphorylation coupling both in cardiomyocytes and in mitochondria, which was associated with the decrease in the rate of consumption of energy resources.
Sobre autores
L. Tsapko
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Autor responsável pela correspondência
Email: lpc@cardio-tomsk.ru
Rússia, Tomsk
S. Afanas’ev
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: lpc@cardio-tomsk.ru
Rússia, Tomsk
