Email this article Influence of Age Factor on Respiratory Control of Isolated Cardiomyocytes and Mitochondria in Rats
- Authors: Tsapko L.P.1, Afanas’ev S.A.1
-
Affiliations:
- Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
- Issue: Vol 167, No 4 (2019)
- Pages: 452-454
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241792
- DOI: https://doi.org/10.1007/s10517-019-04547-4
- ID: 241792
Cite item
Open Access
Access granted
Subscription Access
Abstract
We studied the peculiarities of oxidative and substrate phosphorylation in isolated cardiomyocytes and myocardial mitochondria in 2- and 15-month-old rats. It was shown that age factor reduces the degree of oxidation and phosphorylation coupling both in cardiomyocytes and in mitochondria, which was associated with the decrease in the rate of consumption of energy resources.
About the authors
L. P. Tsapko
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Author for correspondence.
Email: lpc@cardio-tomsk.ru
Russian Federation, Tomsk
S. A. Afanas’ev
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: lpc@cardio-tomsk.ru
Russian Federation, Tomsk
