Effect of Metabolic Stress on Lysosomal Proteolysis in the Liver and Brain of Rats Receiving Q10-Enriched Ration


Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Somente assinantes

Resumo

Activation of lysosomal proteolysis and increased coenzyme Q10 level were revealed in the liver and brain of rats with individual typological features under conditions of food deprivation. Changes in cathepsin B activity in these tissues were different in behaviorally active and passive animals. We observed indirect modulating effect of coenzyme Q10 in the regulation of activity of lysosomal endopeptidases in the brain of animals with different behavior during adaptation to metabolic stress.

Sobre autores

N. Kirbaeva

Federal Research Center of Nutrition and Biotechnology, Russian Academy of Sciences

Autor responsável pela correspondência
Email: n.kirbaeva@gmail.com
Rússia, Moscow

N. Sharanova

V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Email: n.kirbaeva@gmail.com
Rússia, Moscow

V. Zhminchenko

Federal Research Center of Nutrition and Biotechnology, Russian Academy of Sciences

Email: n.kirbaeva@gmail.com
Rússia, Moscow

A. Vasil’ev

Federal Research Center of Nutrition and Biotechnology, Russian Academy of Sciences

Email: n.kirbaeva@gmail.com
Rússia, Moscow


Declaração de direitos autorais © Springer Science+Business Media, LLC, part of Springer Nature, 2018

Este site utiliza cookies

Ao continuar usando nosso site, você concorda com o procedimento de cookies que mantêm o site funcionando normalmente.

Informação sobre cookies