Enviar artigo por via de e-mail Radioprotective Properties of Neomitilan in Experimental Radiation Pneumonia
- Autores: Apanasevich V.1, Plekhova N.1, Lagureva A.1, Goncharov A.1, Kotsyurbii E.1, Plotnikova O.1, Sivoraksha D.1, Tarakova O.2, Molchanova V.3, Luk’yanov P.3
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Afiliações:
- Pacific State Medical University, Ministry of Health of the Russian Federation
- Far-Eastern Federal University, Ministry of Education and Science of the Russian Federation
- G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Division of the Russian Academy of Science
- Edição: Volume 165, Nº 1 (2018)
- Páginas: 40-43
- Seção: Pharmacology and Toxicology
- URL: https://journals.rcsi.science/0007-4888/article/view/239959
- DOI: https://doi.org/10.1007/s10517-018-4094-x
- ID: 239959
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Resumo
The efficiency of neomitilan, a polysaccharide isolated from Crenomytilus grayanus mussels, was studied in experimental model of radiation pneumonia (irradiation of the animal lungs with a total dose of 14 and 28 Gy). Histological study showed that an increase in the number of nucleated components in the lungs of animals subjected to neomitilan inhalation prior to irradiation. Proliferation of bronchial epitheliocytes and the formation of additional lymphoid structures were also revealed in these animals. The absence of a tendency to lung tissue recovery in animals irradiated with 28 Gy is due to extreme radiation toxicity.
Sobre autores
V. Apanasevich
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
N. Plekhova
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
A. Lagureva
Pacific State Medical University, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: sandy767@mail.ru
Rússia, Vladivostok
A. Goncharov
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
E. Kotsyurbii
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
O. Plotnikova
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
D. Sivoraksha
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
O. Tarakova
Far-Eastern Federal University, Ministry of Education and Science of the Russian Federation
Email: sandy767@mail.ru
Rússia, Vladivostok
V. Molchanova
G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Division of the Russian Academy of Science
Email: sandy767@mail.ru
Rússia, Vladivostok
P. Luk’yanov
G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Division of the Russian Academy of Science
Email: sandy767@mail.ru
Rússia, Vladivostok
