Enviar artigo por via de e-mail Pulsed Dendritic Cells for the Therapy of Experimental Glioma
- Autores: Chekhonin I.1, Gurina O.1, Cherepanov S.2, Abakumov M.2, Ionova K.1, Zhigarev D.1, Makarov A.1, Chekhonin V.1,2
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Afiliações:
- V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
- Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
- Edição: Volume 161, Nº 6 (2016)
- Páginas: 792-796
- Seção: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/237786
- DOI: https://doi.org/10.1007/s10517-016-3512-1
- ID: 237786
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Resumo
We obtained the morphologically, cytofluorometrically, and functionally mature dendritic cells from rats that were pulsed with antigens of the C6 glioma tissue extract. The concentrations of angiogenesis antigens (VEGF, VEGFR-1, and VEGFR-2) and periglioma zone proteins (GFAP, connexin 43, and BSAT1) in the pulsing extract were measured by ELISA. Our results drove us to a conclusion that despite mature phenotype of pulsed dendritic cell, the antigenic composition of glioma tissue extracts should be modified.
Sobre autores
I. Chekhonin
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
O. Gurina
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
S. Cherepanov
Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
M. Abakumov
Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
K. Ionova
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
D. Zhigarev
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
A. Makarov
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow
V. Chekhonin
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation; Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
Rússia, Moscow; Moscow
