Oxidative Stress and Catalase Gene

O. A. Ershova; T. A. Bairova; S. I. Kolesnikov; O. V. Kalyuzhnaya; M. A. Darenskaya; L. I. Kolesnikova

doi:10.1007/s10517-016-3424-0

Oxidative Stress and Catalase Gene

Autores: Ershova O.¹, Bairova T.¹, Kolesnikov S.¹, Kalyuzhnaya O.¹, Darenskaya M.¹, Kolesnikova L.¹
Afiliações:
1. Research Center of Family Health and Human Reproduction Problems
Edição: Volume 161, Nº 3 (2016)
Páginas: 400-403
Seção: Genetics
URL: https://journals.rcsi.science/0007-4888/article/view/237459
DOI: https://doi.org/10.1007/s10517-016-3424-0
ID: 237459

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Resumo

We studied the frequency of alleles and genotypes of CAT gene -262C>T polymorphism (rs1001179) in Russian and Buryat adolescents. The frequency of -262T allele was 28.31% in Russians and 16.84% in Buryats (p<0.01). In both ethnic groups, a correlation between the study polymorphism and concentration of diene conjugates was observed. Carriers of TT-genotype of CAT gene-262C>T polymorphism had lower level of diene conjugates than carriers of CT- and CC-genotypes.