Transplantation of Simian Mesenchymal Stem Cells to Baboons with Experimentally Induced Myocardial Infarction

V. Z. Agrba; V. A. Porkhanov; D. D. Karal-ogly; A. V. Leontyuk; A. L. Kovalenko; I. Yu. Sholin; T. E. Gvozdik; I. E. Ignatova; A. A. Agumava; Yu. P. Chuguev; I. A. Gvaramiya; B. A. Lapin

doi:10.1007/s10517-016-3223-7

Transplantation of Simian Mesenchymal Stem Cells to Baboons with Experimentally Induced Myocardial Infarction

Autores: Agrba V.¹, Porkhanov V.¹, Karal-ogly D.¹, Leontyuk A.¹, Kovalenko A.¹, Sholin I.¹, Gvozdik T.¹, Ignatova I.¹, Agumava A.¹, Chuguev Y.¹, Gvaramiya I.¹, Lapin B.¹
Afiliações:
1. Research Institute of Medical Primatology
Edição: Volume 160, Nº 4 (2016)
Páginas: 589-591
Seção: Article
URL: https://journals.rcsi.science/0007-4888/article/view/236821
DOI: https://doi.org/10.1007/s10517-016-3223-7
ID: 236821

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Culture of mesenchymal stem cells isolated from the bone marrow of primates by their characteristics met the requirements of stem cells. It was shown that transplantation of allogeneic mesenchymal stem cells (2 million cells per 1 kg body weight) immediately after ligation of the left anterior descending coronary artery between the middle and upper thirds led to neovascularization and capillarization of the ischemic myocardium.