Local Treatment of Local Staphylococcal Infection with Complex Preparations Based on Metal Nanoparticles in the Experiment


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Аннотация

Antibacterial activity of powdered preparations based on copper and silver nanoparticles was compared with activity of the reference preparation Baneocin on the model of local staphylococcal infection in white rats. The developed preparations exhibited pronounced antibacterial activity against methicillin-resistant S. epidermidis strains in vivo significantly (p<0.001) exceeding that of Baneocin, reduced microbial contamination of the wound on day 5 of study by 2 lg and more in comparison with bacterial load before treatment, and provided effective decontamination of the wound within 7-10 days.

Авторлар туралы

I. Babushkina

Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation

Хат алмасуға жауапты Автор.
Email: 10051968@mail.ru
Ресей, Saratov

I. Mamonova

Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation

Email: 10051968@mail.ru
Ресей, Saratov

V. Ulyanov

Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation

Email: 10051968@mail.ru
Ресей, Saratov

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