Morphological Evaluation of the Tissue Reaction to Subcutaneous Implantation of Decellularized Matrices
- Авторлар: Sotnichenko A.1, Nakokhov R.1, Gubareva E.1, Kuevda E.1, Gumenyuk I.1
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Мекемелер:
- Kuban State Medical University
- Шығарылым: Том 166, № 2 (2018)
- Беттер: 287-292
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240974
- DOI: https://doi.org/10.1007/s10517-018-4334-0
- ID: 240974
Дәйексөз келтіру
Аннотация
Based on the data of morphological analysis, we performed histological evaluation of rat tissue reaction to subcutaneous implantation of decellularized matrices of intrathoracic organs and tissues. Cell composition of the inflammatory infiltrate was analyzed, and the dynamics of macrophage and T and B lymphocyte content was assessed on days 7 and 14 of the experiment. It was found that the reaction to implantation depended not only on the quality of decellularization and efficiency of removal of antigen molecules, but also on the original histological structure and quality of preimplantation processing of the transplant.
Авторлар туралы
A. Sotnichenko
Kuban State Medical University
Хат алмасуға жауапты Автор.
Email: alex24.88@mail.ru
Ресей, Krasnodar
R. Nakokhov
Kuban State Medical University
Email: alex24.88@mail.ru
Ресей, Krasnodar
E. Gubareva
Kuban State Medical University
Email: alex24.88@mail.ru
Ресей, Krasnodar
E. Kuevda
Kuban State Medical University
Email: alex24.88@mail.ru
Ресей, Krasnodar
I. Gumenyuk
Kuban State Medical University
Email: alex24.88@mail.ru
Ресей, Krasnodar