Мақаланы E-mail арқылы жіберу Chronopharmacological Characteristics of the Effect of Hepatoprotectors in Experiment?
- Авторлар: Bunyatyan N.1, Kal’ko E.2, Drogovoz S.2, Kononenko A.2
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Мекемелер:
- I. M. Sechenov First Moscow Medical University, the Ministry of Health of Russia
- National Pharmaceutical University
- Шығарылым: Том 165, № 6 (2018)
- Беттер: 754-757
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240725
- DOI: https://doi.org/10.1007/s10517-018-4258-8
- ID: 240725
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
We studied circadian rhythms of activity of hepatoprotectors (Antral, Carsil, and glutargin) under conditions of acute paracetamol-induced hepatitis simulated in the morning, afternoon, evening, and at night (09.00, 15.00, 21.00, and 03.00). Antral and Carsil exhibited similar chronoprofiles with the maximum hepatoprotective activity at 09.00 and 21.00, while glutargin exhibited circadian pattern opposite and its activity was maximum at 15.00 and 03.00.
Авторлар туралы
N. Bunyatyan
I. M. Sechenov First Moscow Medical University, the Ministry of Health of Russia
Хат алмасуға жауапты Автор.
Email: ndbun@mail.ru
Ресей, Moscow
E. Kal’ko
National Pharmaceutical University
Email: ndbun@mail.ru
Украина, Kharkov
S. Drogovoz
National Pharmaceutical University
Email: ndbun@mail.ru
Украина, Kharkov
A. Kononenko
National Pharmaceutical University
Email: ndbun@mail.ru
Украина, Kharkov
