Мақаланы E-mail арқылы жіберу Algorithm of Molecular and Biological Assessment of the Mechanisms of Sensitivity to Drug Toxicity by the Example of Cyclophosphamide
- Авторлар: Telegin L.1, Sarmanaev S.2, Devichenskii V.2, Tutelyan V.3
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Мекемелер:
- Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences
- Institute for Advanced Studies, Federal Medical-Biological Agency
- Federal Research Centre of Nutrition, Biotechnology and Food Safety
- Шығарылым: Том 164, № 3 (2018)
- Беттер: 324-329
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239578
- DOI: https://doi.org/10.1007/s10517-018-3982-4
- ID: 239578
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Comparative study of the liver, blood, and spleen of DBA/2JSto and BALB/cJLacSto mice sensitive and resistant to acute toxicity of the cyclophosphamide allowed us to reveal basic toxicity biomarkers of this antitumor and immunosuppressive agent. Obtained results can be used for the development of an algorithm for evaluation of toxic effects of drugs and food components.
Авторлар туралы
L. Telegin
Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: tell2003@post.ru
Ресей, Moscow
S. Sarmanaev
Institute for Advanced Studies, Federal Medical-Biological Agency
Email: tell2003@post.ru
Ресей, Moscow
V. Devichenskii
Institute for Advanced Studies, Federal Medical-Biological Agency
Email: tell2003@post.ru
Ресей, Moscow
V. Tutelyan
Federal Research Centre of Nutrition, Biotechnology and Food Safety
Email: tell2003@post.ru
Ресей, Moscow
