Effect of NO Synthase Blockade on Myocardial Contractility of Hypokinetic Rats during Stimulation of β-Adrenoreceptors
- Авторлар: Zaripova R.1, Ziyatdinova N.1, Zefirov T.1
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Мекемелер:
- Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
- Шығарылым: Том 161, № 2 (2016)
- Беттер: 215-217
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237275
- DOI: https://doi.org/10.1007/s10517-016-3378-2
- ID: 237275
Дәйексөз келтіру
Аннотация
Stimulation of β-adrenoreceptors with low (10–8 and 10–7 M) or high (10–6 M) doses of isoproterenol in hypokinetic rats treated with L-NAME (a non-selective blocker of NO synthases) decreased or increased myocardial contractility, respectively. In control rats, all examined doses of isoproterenol used under blockade of NO synthases inhibited myocardial contractility.
Авторлар туралы
R. Zaripova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Ресей, Kazan, Tatarstan
N. Ziyatdinova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Ресей, Kazan, Tatarstan
T. Zefirov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Хат алмасуға жауапты Автор.
Email: zefirovtl@mail.ru
Ресей, Kazan, Tatarstan