Enviar artigo por via de e-mail Effect of NO Synthase Blockade on Myocardial Contractility of Hypokinetic Rats during Stimulation of β-Adrenoreceptors
- Autores: Zaripova R.1, Ziyatdinova N.1, Zefirov T.1
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Afiliações:
- Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
- Edição: Volume 161, Nº 2 (2016)
- Páginas: 215-217
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237275
- DOI: https://doi.org/10.1007/s10517-016-3378-2
- ID: 237275
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Resumo
Stimulation of β-adrenoreceptors with low (10–8 and 10–7 M) or high (10–6 M) doses of isoproterenol in hypokinetic rats treated with L-NAME (a non-selective blocker of NO synthases) decreased or increased myocardial contractility, respectively. In control rats, all examined doses of isoproterenol used under blockade of NO synthases inhibited myocardial contractility.
Sobre autores
R. Zaripova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Rússia, Kazan, Tatarstan
N. Ziyatdinova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Rússia, Kazan, Tatarstan
T. Zefirov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Autor responsável pela correspondência
Email: zefirovtl@mail.ru
Rússia, Kazan, Tatarstan
