Мақаланы E-mail арқылы жіберу Role of Progenitor Cells in Liver Regeneration after Subtotal Resection
- Авторлар: El’chaninov A.1,2,3, Fatkhudinov T.1,2,3, Kananykhina E.1,2, Usman N.1,2, Arutyunyan I.1,2, Makarov A.1,2,3, Bykov A.3, Bolshakova G.2, Sukhikh G.1
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Мекемелер:
- V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
- Institute of Human Morphology
- N. I. Pirogov Russian State Medical University, Ministry of Health of the Russian Federation
- Шығарылым: Том 161, № 1 (2016)
- Беттер: 155-161
- Бөлім: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/237220
- DOI: https://doi.org/10.1007/s10517-016-3367-5
- ID: 237220
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
In the liver of rats subjected to subtotal liver resection (80% organ weight), the expression of sox9 gene and SOX9 protein content increased and cells with hepatocyte morphology expressing SOX9 appeared; the proportion of cells expressing cytokeratin-19 also increased. Based on these data, we cannot completely exclude the involvement of resident progenitor cells and hepatocyte reprogramming in liver regeneration after subtotal resection, however, the contribution of these processes seems to be insignificant. The leading mechanism of liver mass recovery after subtotal resection is proliferation of hepatocytes.
Авторлар туралы
A. El’chaninov
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation; Institute of Human Morphology; N. I. Pirogov Russian State Medical University, Ministry of Health of the Russian Federation
Email: fatkhudinov@gmail.com
Ресей, Moscow; Moscow; Moscow
T. Fatkhudinov
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation; Institute of Human Morphology; N. I. Pirogov Russian State Medical University, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: fatkhudinov@gmail.com
Ресей, Moscow; Moscow; Moscow
E. Kananykhina
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation; Institute of Human Morphology
Email: fatkhudinov@gmail.com
Ресей, Moscow; Moscow
N. Usman
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation; Institute of Human Morphology
Email: fatkhudinov@gmail.com
Ресей, Moscow; Moscow
I. Arutyunyan
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation; Institute of Human Morphology
Email: fatkhudinov@gmail.com
Ресей, Moscow; Moscow
A. Makarov
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation; Institute of Human Morphology; N. I. Pirogov Russian State Medical University, Ministry of Health of the Russian Federation
Email: fatkhudinov@gmail.com
Ресей, Moscow; Moscow; Moscow
A. Bykov
N. I. Pirogov Russian State Medical University, Ministry of Health of the Russian Federation
Email: fatkhudinov@gmail.com
Ресей, Moscow
G. Bolshakova
Institute of Human Morphology
Email: fatkhudinov@gmail.com
Ресей, Moscow
G. Sukhikh
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: fatkhudinov@gmail.com
Ресей, Moscow
