Analysis of Plasma microRNA Associated with Hemolysis


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Аннотация

We analyzed the effect of hemolysis on microRNA profi le of blood plasma. It was found that hemolysis of ~0.05% erythrocytes in a sample signifi cantly affected the concentration of 9 microRNA: hsa-miR-486-5p, hsa-miR-16-5p, hsa-miR-451a, hsa-miR-106a-5p, hsa-miR-17-5p, hsa-miR-93-5p, hsa-miR-20a-5p, hsa-miR-107, and hsa-miR-20b-5p. The effect of hemolysis on plasma content of miR-17 family microRNA was demonstrated.

Авторлар туралы

M. Shkurnikov

BioClinicum Research and Development Center; National Medical Research Radiological Center, Ministry of Health of the Russian Federation

Хат алмасуға жауапты Автор.
Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow; Moscow

E. Knyazev

BioClinicum Research and Development Center

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

K. Fomicheva

National Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

D. Mikhailenko

National Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

K. Nyushko

National Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

E. Saribekyan

National Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

T. Samatov

BioClinicum Research and Development Center

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

B. Alekseev

National Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@imscs.msu.ru
Ресей, Moscow

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