Soft Tissue Regeneration under the Effect of Wound Coating Based on Chitosan (Natural Biopolymer)
- Авторлар: Gladkova E.1, Babushkina I.1, Norkin I.1, Mamonova I.1, Puchin’yan D.1, Konyuchenko E.1
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Мекемелер:
- Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
- Шығарылым: Том 160, № 5 (2016)
- Беттер: 715-717
- Бөлім: Biotechnologies
- URL: https://journals.rcsi.science/0007-4888/article/view/236915
- DOI: https://doi.org/10.1007/s10517-016-3258-9
- ID: 236915
Дәйексөз келтіру
Аннотация
We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and buffer component, the biodegraded wound coating optimizes all phases of the wound process, accelerates by 22-28% the reparative regeneration, and leads to anatomic and functional restoration of injured sites. High absorption capacity recommends its use in the treatment of wounds with profuse exudation.
Авторлар туралы
E. Gladkova
Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: gladckowa.katya@yandex.ru
Ресей, Saratov
I. Babushkina
Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
Email: gladckowa.katya@yandex.ru
Ресей, Saratov
I. Norkin
Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
Email: gladckowa.katya@yandex.ru
Ресей, Saratov
I. Mamonova
Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
Email: gladckowa.katya@yandex.ru
Ресей, Saratov
D. Puchin’yan
Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
Email: gladckowa.katya@yandex.ru
Ресей, Saratov
E. Konyuchenko
Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation
Email: gladckowa.katya@yandex.ru
Ресей, Saratov