Effect of Bone Marrow Multipotent Mesenchymal Stromal Cells on Blood and Lymphatic Vasculature in Uterine Wall of Wistar Rats during Experimental Chronic Metroendometritis
- Authors: Koroleva E.G.1, Dergacheva T.I.1, Shurlygina A.V.1, Poveshchenko O.V.1, Krasil’nikov S.E.2, Konenkov V.I.1
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Affiliations:
- Research Institute of Experimental and Clinical Lymphology, Federal Research Center of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Novosibirsk Regional Clinical Oncology Health Center
- Issue: Vol 165, No 2 (2018)
- Pages: 205-208
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240165
- DOI: https://doi.org/10.1007/s10517-018-4130-x
- ID: 240165
Cite item
Abstract
The study examined the effect of bone marrow multipotent mesenchymal stromal cells and their products secreted into the conditioned medium on uterine microcirculatory bed in Wistar rats during chronic inflammation. The parameters of blood and lymphatic microcirculation in the uterus changed in various directions in relation to the administration routes of biomedical cell product, which is important when the cell therapy is employed in the treatment of inflammatory-degenerative alterations in the lesser pelvis organs.
About the authors
E. G. Koroleva
Research Institute of Experimental and Clinical Lymphology, Federal Research Center of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Russian Federation, Novosibirsk
T. I. Dergacheva
Research Institute of Experimental and Clinical Lymphology, Federal Research Center of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Author for correspondence.
Email: dr-tanja@yandex.ru
Russian Federation, Novosibirsk
A. V. Shurlygina
Research Institute of Experimental and Clinical Lymphology, Federal Research Center of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Russian Federation, Novosibirsk
O. V. Poveshchenko
Research Institute of Experimental and Clinical Lymphology, Federal Research Center of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Russian Federation, Novosibirsk
S. E. Krasil’nikov
Novosibirsk Regional Clinical Oncology Health Center
Email: dr-tanja@yandex.ru
Russian Federation, Novosibirsk
V. I. Konenkov
Research Institute of Experimental and Clinical Lymphology, Federal Research Center of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Russian Federation, Novosibirsk