Influence of “Enriched Environment” on Behavior and Neurogenesis in Mice Selected by Cognitive Trait
- Authors: Tarasova A.Y.1, Perepelkina O.V.1, Lil’p I.G.1, Revishchin A.V.2, Pavlova G.V.1, Poletaeva I.I.1
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Affiliations:
- Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
- Institute of Gene Biology, Russian Academy of Sciences
- Issue: Vol 164, No 5 (2018)
- Pages: 583-586
- Section: Physiology
- URL: https://journals.rcsi.science/0007-4888/article/view/239767
- DOI: https://doi.org/10.1007/s10517-018-4036-7
- ID: 239767
Cite item
Abstract
Mice selected for high score in the extrapolation test (EX line) and kept under conditions of “enriched environment” for 3 months demonstrated changes in locomotor and exploratory activity and enhanced reaction to novelty. The relative brain weight was higher and neurogenesis in the hippocampal fascia dentate was more intensive in this group. In non-selected mice, the changes were similar, but insignificant in many cases.
About the authors
A. Yu. Tarasova
Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
Author for correspondence.
Email: odrima@yandex.ru
Russian Federation, Moscow
O. V. Perepelkina
Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
Email: odrima@yandex.ru
Russian Federation, Moscow
I. G. Lil’p
Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
Email: odrima@yandex.ru
Russian Federation, Moscow
A. V. Revishchin
Institute of Gene Biology, Russian Academy of Sciences
Email: odrima@yandex.ru
Russian Federation, Moscow
G. V. Pavlova
Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
Email: odrima@yandex.ru
Russian Federation, Moscow
I. I. Poletaeva
Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
Email: odrima@yandex.ru
Russian Federation, Moscow