Influence of “Enriched Environment” on Behavior and Neurogenesis in Mice Selected by Cognitive Trait

A. Yu. Tarasova; O. V. Perepelkina; I. G. Lil’p; A. V. Revishchin; G. V. Pavlova; I. I. Poletaeva

doi:10.1007/s10517-018-4036-7

Influence of “Enriched Environment” on Behavior and Neurogenesis in Mice Selected by Cognitive Trait

Authors: Tarasova A.Y.¹, Perepelkina O.V.¹, Lil’p I.G.¹, Revishchin A.V.², Pavlova G.V.¹, Poletaeva I.I.¹
Affiliations:
1. Department of Higher Nervous Activity, Faculty of Biology, M. V. Lomonosov State University
2. Institute of Gene Biology, Russian Academy of Sciences
Issue: Vol 164, No 5 (2018)
Pages: 583-586
Section: Physiology
URL: https://journals.rcsi.science/0007-4888/article/view/239767
DOI: https://doi.org/10.1007/s10517-018-4036-7
ID: 239767

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Abstract

Mice selected for high score in the extrapolation test (EX line) and kept under conditions of “enriched environment” for 3 months demonstrated changes in locomotor and exploratory activity and enhanced reaction to novelty. The relative brain weight was higher and neurogenesis in the hippocampal fascia dentate was more intensive in this group. In non-selected mice, the changes were similar, but insignificant in many cases.