Functional and Biochemical Parameters of Erythrocytes during Mexicor Treatment in Posttraumatic Period after Experimental Blood Loss and Combined Traumatic Brain Injury


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Mexicor treatment (8 mg/kg body weight per day) during the posttraumatic period after concomitant traumatic brain injury and acute blood loss in rats increased electrophoretic mobility and concentration of 2,3-diphosphoglycerate, and reduced malondialdehyde content in erythrocytes. These changes improved hemodynamics and oxygen-transporting function of the blood. The most pronounced effects of Mexicor were observed at the early stages of posttraumatic period.

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A. Deryugina

Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University

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Email: derugina69@yandex.ru
俄罗斯联邦, Nizhny Novgorod

A. Shumilova

Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University

Email: derugina69@yandex.ru
俄罗斯联邦, Nizhny Novgorod

E. Filippenko

Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University

Email: derugina69@yandex.ru
俄罗斯联邦, Nizhny Novgorod

Ya. Galkina

Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University

Email: derugina69@yandex.ru
俄罗斯联邦, Nizhny Novgorod

I. Simutis

Department of Anesthesiology and Reanimatology, Municipal Clinical Hospital No. 40

Email: derugina69@yandex.ru
俄罗斯联邦, Nizhny Novgorod

G. Boyarinov

Department of Anesthesiology and Reanimatology, Faculty of Continuing Medical Education, Nizhny Novgorod State Medical Academy

Email: derugina69@yandex.ru
俄罗斯联邦, Nizhny Novgorod

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