Email this article Functional and Biochemical Parameters of Erythrocytes during Mexicor Treatment in Posttraumatic Period after Experimental Blood Loss and Combined Traumatic Brain Injury
- Authors: Deryugina A.V.1, Shumilova A.V.1, Filippenko E.S.1, Galkina Y.V.1, Simutis I.S.2, Boyarinov G.A.3
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Affiliations:
- Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University
- Department of Anesthesiology and Reanimatology, Municipal Clinical Hospital No. 40
- Department of Anesthesiology and Reanimatology, Faculty of Continuing Medical Education, Nizhny Novgorod State Medical Academy
- Issue: Vol 164, No 1 (2017)
- Pages: 26-29
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239333
- DOI: https://doi.org/10.1007/s10517-017-3918-4
- ID: 239333
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Abstract
Mexicor treatment (8 mg/kg body weight per day) during the posttraumatic period after concomitant traumatic brain injury and acute blood loss in rats increased electrophoretic mobility and concentration of 2,3-diphosphoglycerate, and reduced malondialdehyde content in erythrocytes. These changes improved hemodynamics and oxygen-transporting function of the blood. The most pronounced effects of Mexicor were observed at the early stages of posttraumatic period.
About the authors
A. V. Deryugina
Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University
Author for correspondence.
Email: derugina69@yandex.ru
Russian Federation, Nizhny Novgorod
A. V. Shumilova
Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University
Email: derugina69@yandex.ru
Russian Federation, Nizhny Novgorod
E. S. Filippenko
Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University
Email: derugina69@yandex.ru
Russian Federation, Nizhny Novgorod
Ya. V. Galkina
Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University
Email: derugina69@yandex.ru
Russian Federation, Nizhny Novgorod
I. S. Simutis
Department of Anesthesiology and Reanimatology, Municipal Clinical Hospital No. 40
Email: derugina69@yandex.ru
Russian Federation, Nizhny Novgorod
G. A. Boyarinov
Department of Anesthesiology and Reanimatology, Faculty of Continuing Medical Education, Nizhny Novgorod State Medical Academy
Email: derugina69@yandex.ru
Russian Federation, Nizhny Novgorod
