Effects of Bone Marrow Multipotent Mesenchymal Stromal Cells and Their Secretory Products on Microcirculation in the Broad Ligament of the Uterus of Wistar Rats during Experimental Chronic Genital Inflammation
- Authors: Konenkov V.I.1, Borodin Y.I.1, Dergacheva T.I.1, Shurlygina A.V.2, Tenditnik M.V.2, Starkova E.V.1, Poveshchenko O.V.1, Lykov A.P.1
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Affiliations:
- Research Institute of Clinical and Experimental Lymphology
- Research Institute of Physiology and Fundamental Medicine
- Issue: Vol 163, No 1 (2017)
- Pages: 78-81
- Section: Oncology
- URL: https://journals.rcsi.science/0007-4888/article/view/238657
- DOI: https://doi.org/10.1007/s10517-017-3742-x
- ID: 238657
Cite item
Abstract
Effects of bone marrow multipotent mesenchymal stromal cells and their secretory products released into the conditioned medium on microcirculatory bed in the broad ligament of the uterus were studied in Wistar rats with chronic genital inflammation. Opposite changes in the parameters of microcirculation and lymphatic drainage in the broad ligament of the uterus were observed after administration of cells and conditioned medium via different routes, which should be taken into account during the treatment of inflammatory and degenerative processes in the pelvic organs.
About the authors
V. I. Konenkov
Research Institute of Clinical and Experimental Lymphology
Author for correspondence.
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
Yu. I. Borodin
Research Institute of Clinical and Experimental Lymphology
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
T. I. Dergacheva
Research Institute of Clinical and Experimental Lymphology
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
A. V. Shurlygina
Research Institute of Physiology and Fundamental Medicine
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
M. V. Tenditnik
Research Institute of Physiology and Fundamental Medicine
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
E. V. Starkova
Research Institute of Clinical and Experimental Lymphology
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
O. V. Poveshchenko
Research Institute of Clinical and Experimental Lymphology
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk
A. P. Lykov
Research Institute of Clinical and Experimental Lymphology
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk