Effects of Bone Marrow Multipotent Mesenchymal Stromal Cells and Their Secretory Products on Microcirculation in the Broad Ligament of the Uterus of Wistar Rats during Experimental Chronic Genital Inflammation


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Abstract

Effects of bone marrow multipotent mesenchymal stromal cells and their secretory products released into the conditioned medium on microcirculatory bed in the broad ligament of the uterus were studied in Wistar rats with chronic genital inflammation. Opposite changes in the parameters of microcirculation and lymphatic drainage in the broad ligament of the uterus were observed after administration of cells and conditioned medium via different routes, which should be taken into account during the treatment of inflammatory and degenerative processes in the pelvic organs.

About the authors

V. I. Konenkov

Research Institute of Clinical and Experimental Lymphology

Author for correspondence.
Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

Yu. I. Borodin

Research Institute of Clinical and Experimental Lymphology

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

T. I. Dergacheva

Research Institute of Clinical and Experimental Lymphology

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

A. V. Shurlygina

Research Institute of Physiology and Fundamental Medicine

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

M. V. Tenditnik

Research Institute of Physiology and Fundamental Medicine

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

E. V. Starkova

Research Institute of Clinical and Experimental Lymphology

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

O. V. Poveshchenko

Research Institute of Clinical and Experimental Lymphology

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk

A. P. Lykov

Research Institute of Clinical and Experimental Lymphology

Email: vikonenkov@gmail.com
Russian Federation, Novosibirsk


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