Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures
- Authors: Minin A.S.1,2, Belousova A.V.1,3, Smolyuk L.T.3, Ulitko M.V.1, Uimin M.A.2, Byzov I.V.2
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Affiliations:
- B. N. Eltsin Ural Federal University
- M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences
- Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences
- Issue: Vol 162, No 2 (2016)
- Pages: 248-251
- Section: Biotechnologies
- URL: https://journals.rcsi.science/0007-4888/article/view/238087
- DOI: https://doi.org/10.1007/s10517-016-3587-8
- ID: 238087
Cite item
Abstract
Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nanoparticles into the cell depended on their surface charge: positively charged nanoparticles of this structure penetrated inside, while negatively charged particles were not found in the cells.
About the authors
A. S. Minin
B. N. Eltsin Ural Federal University; M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences
Author for correspondence.
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg; Ekaterinburg
A. V. Belousova
B. N. Eltsin Ural Federal University; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg; Ekaterinburg
L. T. Smolyuk
Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg
M. V. Ulitko
B. N. Eltsin Ural Federal University
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg
M. A. Uimin
M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg
I. V. Byzov
M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg