Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures


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Abstract

Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nanoparticles into the cell depended on their surface charge: positively charged nanoparticles of this structure penetrated inside, while negatively charged particles were not found in the cells.

About the authors

A. S. Minin

B. N. Eltsin Ural Federal University; M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences

Author for correspondence.
Email: calamatica@gmail.com
Russian Federation, Ekaterinburg; Ekaterinburg

A. V. Belousova

B. N. Eltsin Ural Federal University; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences

Email: calamatica@gmail.com
Russian Federation, Ekaterinburg; Ekaterinburg

L. T. Smolyuk

Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences

Email: calamatica@gmail.com
Russian Federation, Ekaterinburg

M. V. Ulitko

B. N. Eltsin Ural Federal University

Email: calamatica@gmail.com
Russian Federation, Ekaterinburg

M. A. Uimin

M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences

Email: calamatica@gmail.com
Russian Federation, Ekaterinburg

I. V. Byzov

M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences

Email: calamatica@gmail.com
Russian Federation, Ekaterinburg


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