Effects of Levofloxacin on Blood Lymphocyte Apoptosis in Patients with Pulmonary Tuberculosis: an In Vitro Study
- 作者: Serebryakova V.1, Urazova O.1, Novitsky V.1, Vengerovskii A.1, Kononova T.1, Vasil’eva O.1, Beresneva A.1
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隶属关系:
- Siberian State Medical University, Ministry of Health of the Russian Federation
- 期: 卷 168, 编号 1 (2019)
- 页面: 109-112
- 栏目: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/242270
- DOI: https://doi.org/10.1007/s10517-019-04659-x
- ID: 242270
如何引用文章
详细
The effects of a fluroquinolone levofloxacin on apoptosis of peripheral blood lymphocytes from patients with infiltrative pulmonary tuberculosis were studied in vitro. It was found that levofloxacin stimulated apoptotic cell death in tuberculosis. Addition of levofloxacin to cell suspension from patients with drug-susceptible form of tuberculosis led to an increase in the number of CD95+ and AnnV+ lymphocytes. In patients with drug-resistant form of tuberculosis, only the number of apoptotic lymphocytes, but not the count of CD95+ cells increased under these conditions.
作者简介
V. Serebryakova
Siberian State Medical University, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
O. Urazova
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
V. Novitsky
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
A. Vengerovskii
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
T. Kononova
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
O. Vasil’eva
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
A. Beresneva
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: serebryakova-val@mail.ru
俄罗斯联邦, Tomsk
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