Effect of Endomorphin-1 on Contractile Activity of Rat Mesenteric Lymphatic Vessels
- Authors: Nechaykina O.V.1, Petunov S.G.1
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Affiliations:
- Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia
- Issue: Vol 168, No 1 (2019)
- Pages: 55-57
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242199
- DOI: https://doi.org/10.1007/s10517-019-04645-3
- ID: 242199
Cite item
Abstract
We studied the effect of endomorphin-1 on isolated mesenteric lymphatic vessels in rats. It was found that endomorphin-1 caused a dose-dependent increase in the contractile activity of lymphangions, which was associated with stimulation of intracellular calcium depots. The observed effect of endomorphin-1 in isolated lymphatic vessels has a complex mechanism; it depends on the concentration of the applied peptide and is probably determined by its interaction with non-opioid receptors
About the authors
O. V. Nechaykina
Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia
Author for correspondence.
Email: olga2278@mail.ru
Russian Federation, Kuzmolovsky, Leningrad Region
S. G. Petunov
Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia
Email: olga2278@mail.ru
Russian Federation, Kuzmolovsky, Leningrad Region